Buy 1P-LSD Blotters Online
1P–LSD which is a novel lysergamide and was first synthesized in 2014. It is the N-propionyl derivative of LSD and a homologue of ALD-52. Given that there is no literature on this material, there arises a great opportunity to study and research its physical and chemical properties. Wholesale supplier and expoter of 1p-lsd in USA.
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1-Propionyl-lysergic acid diethylamide (commonly known as 1P–LSD or 1P-LAD) is a novel semi-synthetic psychedelic substance of the lysergamide chemical class that produces “classical psychedelic” effects reported to be near-identical with those of LSD when administered.
After effects: 6 – 24 hours
Peak: 3 – 5 hours
Come up: 45 – 120 minutes
Onset: 20 – 60 minutes
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1-propionyl-LSD also known as 1P-LSD is a brand new EU LSD analgoue. 100% legal accross most of the EU (do your checks). Buy 1P-LSD Blotters Online
1-Propionyl-d-lysergic acid diethylamide hemitartrate (1P-LSD) has become available as a ‘research chemical’ in the form of blotters and powdered material. This non-controlled derivative of d-lysergic acid diethylamide (LSD) has previously not been described in the published literature despite being closely related to 1-acetyl-LSD (ALD-52), which was developed in the 1950s. This study describes the characterization of 1P-LSD in comparison with LSD using various chromatographic and mass spectrometric methods, infrared and nuclear magnetic resonance spectroscopy. An important feature common to LSD and other serotonergic hallucinogens is that they produce 5-HT2A-receptor activation and induce the head-twitch response (HTR) in rats and mice. In order to assess whether 1P-LSD displays LSD-like properties and activates the 5-HT2A receptor, male C57BL/6 J mice were injected with vehicle (saline) or 1P-LSD (0.025–0.8 mg/kg, IP) and HTR assessed for 30 min using magnetometer coil recordings. It was found that 1P-LSD produced a dose-dependent increase in HTR counts, and that it had ~38% (ED50 = 349.6 nmol/kg) of the potency of LSD (ED50 = 132.8 nmol/kg). Furthermore, HTR was abolished when 1P-LSD administration followed pretreatment with the selective 5-HT2A receptor antagonist M100907 (0.1 mg/kg, SC), which was consistent with the concept that the behavioural response was mediated by activation of the 5-HT2A receptor. These results indicate that 1P-LSD produces LSD-like effects in mice, consistent with its classification as a serotonergic hallucinogen. Nevertheless, the extent to which 1P-LSD might show psychoactive effects in humans similar to LSD remains to be investigated.